夏伟   医学博士，副教授，硕士生导师；现任华中科技大学同济医学院生殖健康研究所党政办公室主任。

电子邮件：tjxiawei@126.com

社会兼职：中华医学会计划生育学分会生育信息学组委员；全国妇幼健康学会生殖免疫专委会理事；湖北省性学会副秘书长；湖北省生殖健康学会理事；湖北省免疫学会生殖免疫专委会常务理事；华中科技大学同济医学院生殖医学中心国家药物临床研究机构秘书；华中科技大学同济医学院生殖医学中心伦理委员会秘书。

学术经历：2008年获华中科技大学同济医学院泌尿外科学博士学位。2015年国家公派访问学者在美国哈佛大学访学1年。长期从事生殖医学科研、教学及临床工作。

学术成果：主持国家自然科学基金项目、省卫计委项目、临床试验研究项目共10余项，作为课题骨干参与20余项重点研发计划、国家科技支撑计划、国家自然科学基金项目等课题研究。以第一或通讯作者发表科研论文20余篇，发表在Fertility&Sterility、Int Journal of Nanomedicine、Andrology、Contraception等国际权威期刊上。授权发明专利1项。参与编写专著《免疫性不孕不育的诊断与治疗》、《男性避孕与节育》、《人类精子学》第二版、《男性生殖道疾病与生育调节技术》、《现代计划生育学》、《性医学学习指导与习题集》。

研究方向：生殖医学基础研究、男性不育基础与临床研究、避孕节育新技术转化医学研究。

主持和重要参与项目：

1. 国家自然科学基金面上项目 《睾丸热激致生精凋亡中CIRBP的作用及分子机制研究》 (主持)  

2. 国家自然科学基金青年项目  《探索MAPK14 (p38MAPK) 蛋白激酶在卵母细胞中的功能》  (主持)  

3. 湖北省卫健委项目  《饮食营养对不孕不育患者辅助生殖技术后结局影响的队列研究》(主持)

4. 国家重点研发计划(子课题） 《配子源性因素对子代健康的影响》(参与)

5. 国家重点研发计划(子课题） 《基于新材料的安全高效新型宫内节育器》(参与)

代表性论文：

1. Xu C, Bao M, Fan X, Huang J, Zhu C, Xia W. EndMT: New findings on the origin of myofibroblasts in endometrial fibrosis of intrauterine adhesions. Reprod Biol Endocrinol. 2022 Jan 7;20(1):9.

2. Liu, Heyu; Xu, Chengcheng; Bao, Meng; Huang, Jin; Zou, Liping; Fan, Xiaorong; Zhu, Changhong; Xia, Wei ; Cold-inducible RNA-binding protein regulates cyclin B1 against spermatogenesis arrest caused by heat stress, Andrology, 2022, 10(2): 392-403

3. Zou, Liping; Cheng, Guiping; Xu, Chengcheng; Liu, Heyu; Wang, Yingying; Li, Nianyu; Fan,Xiaorong; Zhu, Changhong; Xia, Wei ; Copper Nanoparticles Induce Oxidative Stress via the Heme Oxygenase I Signaling Pathway in vitro Studies, INTERNATIONAL JOURNAL OF NANOMEDICINE, 2021, 16: 1565-1573

4. Zou L, Cheng G, Xu C, Liu H, Wang Y, Li N, Zhu C, Xia W.The role of miR-128-3p through MAPK14 activation in the apoptosis of GC2 spermatocyte cell line following heat stress.Andrology. 2021 Mar;9(2):665-672.

5. Fan X, Huang J, Xu C, Bao M, Xia W, Zhu C.Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper. Mol Hum Reprod. 2021 Sep 1;27(9):gaab052. doi: 10.1093/molehr/gaab052.

6. Wu, Yan-Qing; Rao, Meng; Hu, Shi-Fu; Ke, Dan-Dan; Zhu, Chang-Hong; Xia, Wei ; Effect of transient scrotal hyperthermia on human sperm: an iTRAQ-based proteomic analysis, Reproductive Biology and Endocrinology, 2020, 18(1): 83

7. Xu C, Ke D, Zou L, Li N, Wang Y, Fan X, Zhu C, Xia W. Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury. Reprod Fertil Dev. 2020 Dec;32(18):1357-1364..

8. Wang YY, Hu SF, Rao M, Xia XP, Xia W, Zhu CH. Antifertility effectiveness of a novel polymer matrix composite and its influence on the endometrium in rhesus macaques (Macaca mulatta).Contraception. 2019 Aug;100(2):132-136

9. Cheng G,Ke D, Rao M, Hu S, Wang Y, Zhou F, Liu H, Zhu C, Xia W.Effects of cold-inducible RNA-binding protein on the proliferation and apoptosis of spermatogenic cells in vitro following heat stress.Reprod Fertil Dev. 2019 Apr;31(5):953-961.

10.Rao M, Zhou F, Tang L, Zeng Z, Hu S, Wang Y, Ke D, Cheng G, Xia W, Zhang L, Zhu C.Follicular fluid humanin concentration is related to ovarian reserve markers and clinical pregnancy after IVF-ICSI: a pilot study.Reprod Biomed Online. 2019 Jan;38(1):108-117.

11.Hu LX, Hu SF, Rao M, Yang J, Lei H, Duan Z, Xia W, Zhu CStudies of acute and subchronic systemic toxicity associated with a copper/low-density polyethylene nanocomposite intrauterine device..Int J Nanomedicine. 2018 Aug 31;13:4913-4926.

12.Hu S, Wang Y, Ke D, Zhou F, Cheng G, Xia W, Zhu C.Antifertility effectiveness of a novel copper-containing intrauterine device material and its i nfluence on the endometrial environment in rats.Mater Sci Eng C Mater Biol Appl. 2018 Aug 1;89:444-455.

13.Yang J, Hu S, Rao M, Hu L, Lei H, Wu Y, Wang Y, Ke D, Xia W, Zhu CH.Copper nanoparticle-induced ovarian injury, follicular atresia, apoptosis, and gene expression alterations in female rats. Int J Nanomedicine. 2017 Aug 18;12:5959-5971.

14.Xia W, Chiu YH, Afeiche MC, Williams PL, Ford JB, Tanrikut C, Souter I, Hauser R, Chavarro JE; EARTH study team.Impact of men's dairy intake on assisted reproductive technology outcomes among couples attending a fertility clinic.  Andrology. 2016 Mar;4(2):277-83.

15.Xia W, Chiu YH, Williams PL, Gaskins AJ, Toth TL, Tanrikut C, Hauser R, Chavarro JE.Men's meat intake and treatment outcomes among couples undergoing assisted reproduction.Fertil Steril. 2015 Oct;104(4):972-979.

16..Rao M, Meng TQ, Hu SH, Guan HT, Wei QY, Xia W, Zhu CH, Xiong CL.Evaluation of semen quality in 1808 university students, from Wuhan, Central China Asian J Androl.2015 Jan-Feb;17(1):111-6.