李自立 博士
学习及工作经历
2006.09-2010.06 湖南师范大学
2010.09-2013.06 湖南师范大学
2013.07-2016.05 人类干细胞国家工程研究中心
2017.09-2020.06 华中科技大学同济医学院生殖健康研究所
研究方向:
多能干细胞向生殖细胞诱导,及诱导过程中分子机制研究。
发表论文:
1. Zili Li, Fang Fang, Qian Zhao, et al. Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells. Stem Cell Res Ther. 2019 Nov 15;10(1):324
2. Fang Fang, Zili Li, Qian Zhao, et al. Induced Pluripotent Stem Cells Derived From Two Idiopathic Azoospermia Patients Display Compromised Differentiation Potential for Primordial Germ Cell Fate. Front. Cell Dev. Biol., 25 June 2020
3. Xiaotong Wang, Shiming Xie, Zili Li, et al. Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene. Stem Cell Research. 2020 Jan, 42:101703
4. Fang Fang, Zili Li, Qian Zhao, et al. Human induced pluripotent stem cells and male infertility: an overview of current progress and perspectives. Human Reproduction. 2018 Feb 1; 33(2):188-195
5. Fang Fang, Zili Li, Qian Zhao, et al. Derivation of human induced pluripotent stem cell line (HUSTi001-A) from a 40-year-old patient with idiopathic infertility. Stem Cell Research. 2018 Mar, 27:136-139